Role of Vitamin E in Improving Pain Severity in Cyclical Mastalgia in Adolescent Women:Aprospective Study

Aims: To study the efficacy of vitamin E in improving pain severity in cyclical mastalgia in adolescent women. Materials and Methods:In a prospective trial of 194 patients suffering from cyclic mastalgia were advised 400 IU of vitamin E daily for 2 month. Written informed consent was obtained from all participants. Severity of breast pain was evaluated by the Cardiff breast pain score during one menstrual cycle before and two menstrual cycle after the intervention Results: There was significant difference in the mean severity of cyclic mastalgia during one menstrual cycle before the intervention vitamin E (9.1 ± 2.1), but the difference was significant during the first cycle (4.9± 1.5) and second cycle (1.5± 1.1 )after the intervention. There was decreasing trend in pain severity score and remarkable improvement in the second cycle . Conclusions: From the results of this study,regimens containing vitamin E has an excellent improvement in reducing breast pain severity in cyclic mastalgia.